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Relationship between COVID19 and inhaling oxygen

Jul 08, 2020

Its main pathogenesis is that inflammatory secretions or exudates are abundantly filled in the lung interstitium and alveoli, thus it blocks fresh air from entering the alveoli and exchanging carbon dioxide in the body, resulting in the body's hypoxia and even multiple organ failure to death. At present, there are no special drugs against the pneumonia. More symptomatic supportive therapy is used, Oxygen inhalation is a very important symptomatic treatment measure throughout the treatment of pneumonia.


One.  Why would it be hypoxic

The main function of the lung: complete the gas exchange of oxygen and carbon dioxide.

The lungs are the first gateway for fresh oxygen from the outside to enter the body. Oxygen enters the lungs with breathing, and exchanges with carbon dioxide through the capillary network of the alveolar wall,this exchange is a physical diffusion process under the effect of oxygen or carbon dioxide partial pressure difference, from the pulmonary vein (pulmonary circulation) into the heart and then from the aorta (systemic circulation) transport oxygen-rich blood to various organs and tissues of the body.A healthy adult's breathing capacity is 450-500ml at a time, about 9 liters of air per minute, about 12960 liters of air per day, equivalent to 16.8 kg, the purpose of inhaling so much air is to ingest about 3.5 kg of oxygen . The quality of lung function directly determines the amount of gas exchange. The greater the vital capacity, the more oxygen is inhaled, the stronger the alveolar diffusion function, and the healthier the person.


Two.  Hypoxia monitoring

1.Oxyhemoglobin saturation(SaO2)

Refers to the proportion of oxygen and hemoglobin,it is the most widely used and most easily obtained data,it reflects the combined amount of oxygen,the advantage is that it can be continuously monitored, but it is easily interfered by external factors, in theory, it can never reach 100% saturation. Normal people are generally 95%-100%, less than 94% can be regarded as hypoxia, SaO2<80%, can basically be diagnosed as hypoxemia, SaO2: 60%-80%, suggesting obvious hypoxemia, SaO2<60%, suggesting severe hypoxemia. The finger oximeter most commonly used in general medical clinic, it has the characteristics of easy operation, non-invasiveness, precision and portability.


2. Blood gas analysis

Arterial oxygen partial pressure (PaO2) refers to the amount of physically dissolved oxygen in the blood,after combining oxygen into the body, it must first dissociate into dissolved oxygen before it can be used by tissue cells,it can objectively reflect the body's hypoxic state at the time, but it cannot be continuously and dynamically observed and Need to draw blood to complete. The normal value is 80-100mmHg, usually PaO2 < 60mmHg can be diagnosed as hypoxemia, PaO2< 50mmHg indicates the presence of respiratory failure, PaO2< 40mmHg indicates severe hypoxia, PaO2< 30mmHg indicates life-threatening. PaO2 will decrease with age, and it can be considered as hypoxemia when it is below the lower limit of the same age.



Three.  Advice for inhaling oxygen

1. The purpose of inhaling oxygen

It includes four aspects:

1. Maintain normal physiological indexes of blood oxygen saturation

2. Protect organ function

3. Repair organ damage due to hypoxia

4. Reduce inflammatory exudation

5. Enhance human immunity

2. How to inhale oxygen

Inhaling oxygen by nebulizer:Germany reported that the nebulization method was used to cure 4 patients with new coronary pneumonia in a short time, if nebulized oxygen therapy is used, it may bring more benefits to the patients. Drugs can be delivered directly to the respiratory tract and alveoli by nebulization. Longfian oxygen generator is equipped with nebulizer function, supplying oxygen+nebulizer,One machine for two purposes


Inhaling oxygen by high flow:It is suitable for severely ill patients with weak breathing, and has achieved ideal results in the treatment of new coronary pneumonia. It is better to rest for 5 minutes after inhaing oxygen every 1 to 2 hours. The 10 lift flow  medical oxygen generator developed by Longfian company is widely used in high-flow oxygen therapy.


3. Patients that infect coronavirus must still insist on oxygen therapy after recovery

Most patients think that everything will be fine after rehabilitation, in fact, the patients have already suffered damage to their body organs during treatment, especially after lung injury, which will indirectly affect the lack of oxygen in other organs,if oxygen is not supplied in time, it will lead to reduced organ function, and even worse, there will be inflammation or failure. Therefore, after discharge from the hospital, we should insist on the recovery of oxygen therapy, the home oxygen generator has become an essential medical device for family health.